Keyword

TrkA

Description: TrkA is a neurotrophin receptor encoded by the NTRK1 gene that mediates nerve growth factor signaling in nervous system cells.

Primary topic: Nerve injury and regeneration (31%)

Wikidata ID: wiki/Q14897694

OpenAlex ID: keywords/trka

Adult rat and human bone marrow stromal cells differentiate into neurons

2000 · Dale Woodbury, Emily J. Schwarz, et al. · Journal of Neuroscience Research · 2,434

Functions of the neurotrophins during nervous system development: What the knockouts are teaching us

1994 · William D. Snider · Cell · 1,428

The Trk family of neurotrophin receptors

1994 · Mariano Barbacid · Journal of Neurobiology · 1,281

Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition

2001 · Huai-hu Chuang, Elizabeth D. Prescott, et al. · Nature · 1,258

The cholinergic system in aging and neuronal degeneration

2010 · Reinhard Schliebs, Thomas Arendt · Behavioural Brain Research · 1,044

Sortilin is essential for proNGF-induced neuronal cell death

2004 · Anders Nykjaer, Ramee Lee, et al. · Nature · 962

Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum

1999 · Lori Sussel, Oscar Marin, et al. · Development · 872

Induction of Apoptosis by the Low-Affinity NGF Receptor

1993 · Shahrooz Rabizadeh, Justin Oh, et al. · Science · 782

Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75

1996 · Patrizia Casaccia-Bonnefil, Bruce D. Carter, et al. · Nature · 764

NGF rapidly increases membrane expression of TRPV1 heat‐gated ion channels

2005 · Xuming Zhang, Jiehong Huang, et al. · The EMBO Journal · 750

Induction of cell death by endogenous nerve growth factor through its p75 receptor

1996 · José María Frade, Alfredo Rodríguez-Tébar, et al. · Nature · 743

IB4-Binding DRG Neurons Switch from NGF to GDNF Dependence in Early Postnatal Life

1997 · D.C Molliver, D.E Wright, et al. · Neuron · 735

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Distinct expression of TRPM8, TRPA1, and TRPV1 mRNAs in rat primary afferent neurons with aδ/c‐fibers and colocalization with trk receptors

2005 · Kimiko Kobayashi, Tetsuo Fukuoka, et al. · The Journal of Comparative Neurology · 729

Selective Activation of NF-κB by Nerve Growth Factor Through the Neurotrophin Receptor p75

1996 · Bruce D. Carter, Christian Kaltschmidt, et al. · Science · 658

The nerve growth factor family of receptors

1992 · Susan O. Meakin, Eric M. Shooter · Trends in Neurosciences · 658

Mutations in the TRKA/NGF receptor gene in patients with congenital insensitivity to pain with anhidrosis

1996 · Yasuhiro Indo, Motoko Tsuruta, et al. · Nature Genetics · 646

TRKing Down an Old Oncogene in a New Era of Targeted Therapy

2014 · Aria Vaishnavi, Anh T. Le, et al. · Cancer Discovery · 642

Immunocytochemical Localization of trkA Receptors in Chemically Identified Subgroups of Adult Rat Sensory Neurons

1995 · S. Averill, S. B. McMahon, et al. · European Journal of Neuroscience · 629

NTRK gene fusions as novel targets of cancer therapy across multiple tumour types

2016 · Alessio Amatu, Andrea Sartore-Bianchi, et al. · ESMO Open · 602

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Cholinergic system during the progression of Alzheimer’s disease: therapeutic implications

2008 · Elliott J Mufson, Scott E Counts, et al. · Expert Review of Neurotherapeutics · 587

Signal transduction by the neutrophin receptors

1997 · David R Kaplan, Freda D Miller · Current Opinion in Cell Biology · 583

Expression and coexpression of Trk receptors in subpopulations of adult primary sensory neurons projecting to identified peripheral targets

1994 · Stephen B. McMahon, Mark P. Armanini, et al. · Neuron · 582

IL‐17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL‐17F, and implications for receptor binding

2001 · Sarah G. Hymowitz, Ellen H. Filvaroff, et al. · The EMBO Journal · 547

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Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: Developmental culling and cancer

2005 · Sungwoo Lee, Eijiro Nakamura, et al. · Cancer Cell · 529

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Novel roles for neurotrophins are suggested by BDNF and NT-3 mRNA expression in developing neurons

1992 · Leslayann C. Schecterson, Mark Bothwell · Neuron · 521

Works count: 5,554

Citation count: 197,500