Keyword

TRPC6

Description: TRPC6 is a protein encoded by the human TRPC6 gene that forms a calcium-permeable ion channel studied in cellular physiology and disease.

Primary topic: Ion Channels and Receptors (39%)

Wikidata ID: wiki/Q14914578

OpenAlex ID: keywords/trpc6

Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol

1999 · Thomas Hofmann, Alexander G. Obukhov, et al. · Nature · 1,495

A Mutation in the TRPC6 Cation Channel Causes Familial Focal Segmental Glomerulosclerosis

2005 · Michelle P. Winn, Peter J. Conlon, et al. · Science · 1,104

TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function

2005 · Jochen Reiser, Krishna R Polu, et al. · Nature Genetics · 863

Subunit composition of mammalian transient receptor potential channels in living cells

2002 · Thomas Hofmann, Michael Schaefer, et al. · Proceedings of the National Academy of Sciences · 743

Calcium signaling in platelets

2009 · D. VARGA‐SZABO, A. BRAUN, et al. · Journal of Thrombosis and Haemostasis · 563

TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling

2006 · Koichiro Kuwahara, Yanggan Wang, et al. · Journal of Clinical Investigation · 561

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A common mechanism underlies stretch activation and receptor activation of TRPC6 channels

2006 · Maria A. Spassova, Thamara Hewavitharana, et al. · Proceedings of the National Academy of Sciences · 517

2-Aminoethoxydiphenyl Borate Is a Common Activator of TRPV1, TRPV2, and TRPV3

2004 · Hong-Zhen Hu, Qihai Gu, et al. · Journal of Biological Chemistry · 517

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Increased Vascular Smooth Muscle Contractility in TRPC6−/− Mice

2005 · Alexander Dietrich, Michael Mederos y Schnitzler, et al. · Molecular and Cellular Biology · 513

Transient Receptor Potential Channels Regulate Myogenic Tone of Resistance Arteries

2002 · Donald G. Welsh, Anthony D. Morielli, et al. · Circulation Research · 512

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STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels

2007 · Joseph P. Yuan, Weizhong Zeng, et al. · Nature Cell Biology · 502

Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factor

2005 · Yan Li, Yi-Chang Jia, et al. · Nature · 450

Genetic determinants of daytime napping and effects on cardiometabolic health

2021 · Hassan S. Dashti, Iyas Daghlas, et al. · Nature Communications · 446

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Enhanced expression of transient receptor potential channels in idiopathic pulmonary arterial hypertension

2004 · Ying Yu, Ivana Fantozzi, et al. · Proceedings of the National Academy of Sciences · 430

Formation of Novel TRPC Channels by Complex Subunit Interactions in Embryonic Brain

2003 · Carsten Strübing, Grigory Krapivinsky, et al. · Journal of Biological Chemistry · 423

TRPC3 and TRPC6 are essential for angiotensin II‐induced cardiac hypertrophy

2006 · Naoya Onohara, Motohiro Nishida, et al. · The EMBO Journal · 411

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Research Progress of Polycyclic Polyprenylated Acylphloroglucinols

2018 · Xing-Wei Yang, Robert B. Grossman, et al. · Chemical Reviews · 373

Transient Receptor Potential Channels in Cardiovascular Function and Disease

2006 · Ryuji Inoue, Lars Jørn Jensen, et al. · Circulation Research · 367

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A TRPC6-Dependent Pathway for Myofibroblast Transdifferentiation and Wound Healing In Vivo

2012 · Jennifer Davis, Adam R. Burr, et al. · Developmental Cell · 358

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Chronic Hypoxia–Induced Upregulation of Store-Operated and Receptor-Operated Ca 2+ Channels in Pulmonary Arterial Smooth Muscle Cells

2004 · Mo-Jun Lin, George P.H. Leung, et al. · Circulation Research · 358

TRP channels in cancer

2007 · Natalia Prevarskaya, Lei Zhang, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 355

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Hypoxia Inducible Factor 1 Mediates Hypoxia-Induced TRPC Expression and Elevated Intracellular Ca 2+ in Pulmonary Arterial Smooth Muscle Cells

2006 · Jian Wang, Letitia Weigand, et al. · Circulation Research · 345

Involvement of TRPC in the abnormal calcium influx observed in dystrophic ( mdx ) mouse skeletal muscle fibers

2002 · Clarisse Vandebrouck, Dominique Martin, et al. · The Journal of Cell Biology · 344

PDGF stimulates pulmonary vascular smooth muscle cell proliferation by upregulating TRPC6 expression

2003 · Ying Yu, Michele Sweeney, et al. · American Journal of Physiology-Cell Physiology · 337

Tissue-specific expression of TRP channel genes in the mouse and its variation in three different mouse strains

2006 · Christiane Kunert-Keil, Frederike Bisping, et al. · BMC Genomics · 330

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Works count: 2,391

Citation count: 72,620