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Keyword

TRPM2

Description: TRPM2 is a calcium-permeable transient receptor potential ion channel involved in cellular calcium signaling, temperature sensing, and immune responses.
OpenAlex ID: keywords/trpm2
The extracellular matrix as a cell survival factor.
1993 · J E Meredith, B Fazeli, et al. · Molecular Biology of the Cell · 1,526
Calcium, ischemia and excitotoxicity
2010 · Kinga Szydlowska, Michael Tymianski · Cell Calcium · 763
TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration
2008 · Shinichiro Yamamoto, Shunichi Shimizu, et al. · Nature Medicine · 622
Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation.
1990 · N Kyprianou, H F English, et al. · PubMed · 478
TRPM2 activation by cyclic ADP‐ribose at body temperature is involved in insulin secretion
2006 · Kazuya Togashi, Yuji Hara, et al. · The EMBO Journal · 460
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Programmed cell death during regression of the MCF-7 human breast cancer following estrogen ablation.
1991 · N Kyprianou, H F English, et al. · PubMed · 422
Expression of Transforming Growth Factor-β in the Rat Ventral Prostate during Castration-Induced Programmed Cell Death
1989 · Natasha Kyprianou, John T. Isaacs · Molecular Endocrinology · 410
The TRPM2 channel is a hypothalamic heat sensor that limits fever and can drive hypothermia
2016 · Kun Song, Hong Wang, et al. · Science · 390
TRPM2 links oxidative stress to NLRP3 inflammasome activation
2013 · Zhenyu Zhong, Yougang Zhai, et al. · Nature Communications · 375
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Tissue Distribution Profiles of the Human TRPM Cation Channel Family
2006 · ELENA FONFRIA, PAUL R. MURDOCK, et al. · Journal of Receptors and Signal Transduction · 369
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Accumulation of Free ADP-ribose from Mitochondria Mediates Oxidative Stress-induced Gating of TRPM2 Cation Channels
2004 · Anne-Laure Perraud, Christina L. Takanishi, et al. · Journal of Biological Chemistry · 358
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Vinclozolin andp,p′-DDE Alter Androgen-Dependent Gene Expression:In VivoConfirmation of an Androgen Receptor-Mediated Mechanism
1997 · William R. Kelce, Christy R. Lambright, et al. · Toxicology and Applied Pharmacology · 352
Cyclic ADP-Ribose and Hydrogen Peroxide Synergize with ADP-Ribose in the Activation of TRPM2 Channels
2005 · Martin Kolisek, Andreas Beck, et al. · Molecular Cell · 340
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Plasma-activated medium induces A549 cell injury via a spiral apoptotic cascade involving the mitochondrial–nuclear network
2014 · Tetsuo Adachi, Hiromasa Tanaka, et al. · Free Radical Biology and Medicine · 334
New Molecular Mechanisms on the Activation of TRPM2 Channels by Oxidative Stress and ADP-Ribose
2007 · Mustafa Nazıroğlu · Neurochemical Research · 322
Regulation of Pain and Itch by TRP Channels
2017 · Carlene Moore, Rupali Gupta, et al. · Neuroscience Bulletin · 307
TRPM2 Functions as a Lysosomal Ca2+-Release Channel in β Cells
2009 · Ingo Lange, Shinichiro Yamamoto, et al. · Science Signaling · 295
The TRPM2 ion channel is required for sensitivity to warmth
2016 · Chun-Hsiang Tan, Peter A. McNaughton · Nature · 294
Critical Intracellular Ca2+ Dependence of Transient Receptor Potential Melastatin 2 (TRPM2) Cation Channel Activation
2003 · Damian McHugh, Richard Flemming, et al. · Journal of Biological Chemistry · 294
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Deficiency of TRPM2 leads to embryonic neurogenesis defects in hyperthermia
2020 · Yanxin Li, Jianwei Jiao · Science Advances · 290
TRPM2: a multifunctional ion channel for calcium signalling
2010 · Adriana Sumoza‐Toledo, Reinhold Penner · The Journal of Physiology · 288
TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP‐ribose) polymerase
2004 · Elena Fonfria, Ian C B Marshall, et al. · British Journal of Pharmacology · 283
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Molecular genetics of bipolar disorder and depression
2007 · TADAFUMI KATO · Psychiatry and Clinical Neurosciences · 282
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Hydrogen peroxide and ADP-ribose induce TRPM2-mediated calcium influx and cation currents in microglia
2004 · Robert Kraft, Christian Grimm, et al. · American Journal of Physiology-Cell Physiology · 281
Functional expression of transient receptor potential melastatin- and vanilloid-related channels in pulmonary arterial and aortic smooth muscle
2006 · Xiao-Ru Yang, Mo-Jun Lin, et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 278
Works count: 2,089
Citation count: 58,690
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