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Keyword

TRPM6

Description: TRPM6 is a magnesium-permeable ion channel protein involved in magnesium homeostasis, particularly in the kidney and intestine.
Wikidata ID: wiki/Q14914571
OpenAlex ID: keywords/trpm6
Magnesium in Man: Implications for Health and Disease
2014 · Jeroen H. F. de Baaij, Joost G. J. Hoenderop, et al. · Physiological Reviews · 1,726
Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene family
2002 · Karl P. Schlingmann, Stefanie Weber, et al. · Nature Genetics · 793
TRPM6 Forms the Mg2+ Influx Channel Involved in Intestinal and Renal Mg2+ Absorption
2003 · Thomas Voets, Bernd Nilius, et al. · Journal of Biological Chemistry · 635
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Mutation of TRPM6 causes familial hypomagnesemia with secondary hypocalcemia
2002 · Roxanne Y. Walder, Daniel Landau, et al. · Nature Genetics · 573
Enhanced passive Ca2+ reabsorption and reduced Mg2+ channel abundance explains thiazide-induced hypocalciuria and hypomagnesemia
2005 · Tom Nijenhuis, Volker Vallon, et al. · Journal of Clinical Investigation · 488
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Functional Characterization of Homo- and Heteromeric Channel Kinases TRPM6 and TRPM7
2006 · Mingjiang Li, Jianmin Jiang, et al. · The Journal of General Physiology · 383
Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia
2004 · Vladimir Chubanov, Siegfried Waldegger, et al. · Proceedings of the National Academy of Sciences · 377
Tissue Distribution Profiles of the Human TRPM Cation Channel Family
2006 · ELENA FONFRIA, PAUL R. MURDOCK, et al. · Journal of Receptors and Signal Transduction · 369
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Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia
2007 · Wouter M. Tiel Groenestege, Stéphanie Thébault, et al. · Journal of Clinical Investigation · 357
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Hypomagnesemia in Type 2 Diabetes: A Vicious Circle?
2015 · Lisanne M.M. Gommers, Joost G.J. Hoenderop, et al. · Diabetes · 336
TRPM6 and TRPM7—Gatekeepers of human magnesium metabolism
2007 · Karl P. Schlingmann, Siegfried Waldegger, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 273
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Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system
2011 · Peter Holzer · Pharmacology & Therapeutics · 245
The Epithelial Mg2+ Channel Transient Receptor Potential Melastatin 6 Is Regulated by Dietary Mg2+ Content and Estrogens
2006 · Wouter M. Tiel Groenestege, Joost G. Hoenderop, et al. · Journal of the American Society of Nephrology · 242
Genome-Wide Association Studies of Serum Magnesium, Potassium, and Sodium Concentrations Identify Six Loci Influencing Serum Magnesium Levels
2010 · Tamra E. Meyer, Germaine C. Verwoert, et al. · PLoS Genetics · 241
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Insights into the molecular nature of magnesium homeostasis
2004 · Martin Konrad, Karl P. Schlingmann, et al. · American Journal of Physiology-Renal Physiology · 233
ThermoTRP channels as modular proteins with allosteric gating
2007 · Ramon Latorre, Sebastian Brauchi, et al. · Cell Calcium · 216
The Channel Kinases TRPM6 and TRPM7 Are Functionally Nonredundant
2005 · Carsten Schmitz, Maxim V. Dorovkov, et al. · Journal of Biological Chemistry · 215
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Downregulation of Ca2+ and Mg2+ Transport Proteins in the Kidney Explains Tacrolimus (FK506)-Induced Hypercalciuria and Hypomagnesemia
2004 · Tom Nijenhuis, Joost G.J. Hoenderop, et al. · Journal of the American Society of Nephrology · 204
Molecular Determinants of Mg2+ and Ca2+ Permeability and pH Sensitivity in TRPM6 and TRPM7
2007 · Mingjiang Li, Jianyang Du, et al. · Journal of Biological Chemistry · 191
Novel TRPM6 Mutations in 21 Families with Primary Hypomagnesemia and Secondary Hypocalcemia
2005 · Karl P. Schlingmann, Martin C. Sassen, et al. · Journal of the American Society of Nephrology · 187
Epithelial Ca2+ and Mg2+ Channels in Health and Disease
2004 · Joost G.J. Hoenderop, René J.M. Bindels · Journal of the American Society of Nephrology · 186
Genetic causes of hypomagnesemia, a clinical overview
2016 · Daan H. H. M Viering, Jeroen H. F. de Baaij, et al. · Pediatric Nephrology · 180
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EGF Increases TRPM6 Activity and Surface Expression
2008 · Ste[Combining Acute Accent]phanie Thebault, R. Todd Alexander, et al. · Journal of the American Society of Nephrology · 178
The mammalian melastatin-related transient receptor potential cation channels: an overview
2005 · Robert Kraft, Christian Harteneck · Pflügers Archiv - European Journal of Physiology · 173
Acid-Base Status Determines the Renal Expression of Ca2+ and Mg2+ Transport Proteins
2006 · Tom Nijenhuis, Kirsten Y. Renkema, et al. · Journal of the American Society of Nephrology · 167
Works count: 637
Citation count: 22,620
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