Keyword

TRPM7

Description: A gene encoding a membrane protein that functions as a magnesium-permeable ion channel and protein kinase, studied in cellular signaling and physiology.

Primary topic: Ion Channels and Receptors (38%)

Wikidata ID: wiki/Q15327611

OpenAlex ID: keywords/trpm7

Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

2013 · Zhenyu Cai, Siriporn Jitkaew, et al. · Nature Cell Biology · 1,314

Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats

2016 · Yifeng Zhang, Jiankun Xu, et al. · Nature Medicine · 1,047

Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene family

2002 · Karl P. Schlingmann, Stefanie Weber, et al. · Nature Genetics · 793

A Key Role for TRPM7 Channels in Anoxic Neuronal Death

2003 · Michelle Aarts, Koji Iihara, et al. · Cell · 782

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Calcium, ischemia and excitotoxicity

2010 · Kinga Szydlowska, Michael Tymianski · Cell Calcium · 763

Regulation of Vertebrate Cellular Mg2+ Homeostasis by TRPM7

2003 · Carsten Schmitz, Anne-Laure Perraud, et al. · Cell · 727

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Calcium flickers steer cell migration

2008 · Chaoliang Wei, Xianhua Wang, et al. · Nature · 611

The functional network of ion channels in T lymphocytes

2009 · Michael D. Cahalan, K. George Chandy · Immunological Reviews · 599

TRPM7 Provides an Ion Channel Mechanism for Cellular Entry of Trace Metal Ions

2002 · Mahealani K. Monteilh-Zoller, Meredith C. Hermosura, et al. · The Journal of General Physiology · 518

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The TRPM7 channel is inactivated by PIP2 hydrolysis

2002 · Loren W. Runnels, Lixia Yue, et al. · Nature Cell Biology · 516

Deletion of Trpm7 Disrupts Embryonic Development and Thymopoiesis Without Altering Mg 2+ Homeostasis

2008 · Jie Jin, Bimal N. Desai, et al. · Science · 416

TRPM7 kinase-mediated immunomodulation in macrophage plays a central role in magnesium ion-induced bone regeneration

2021 · Wei Qiao, Karen H. M. Wong, et al. · Nature Communications · 397

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Functional Characterization of Homo- and Heteromeric Channel Kinases TRPM6 and TRPM7

2006 · Mingjiang Li, Jianmin Jiang, et al. · The Journal of General Physiology · 383

Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia

2004 · Vladimir Chubanov, Siegfried Waldegger, et al. · Proceedings of the National Academy of Sciences · 377

Tissue Distribution Profiles of the Human TRPM Cation Channel Family

2006 · ELENA FONFRIA, PAUL R. MURDOCK, et al. · Journal of Receptors and Signal Transduction · 369

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Transient Receptor Potential Channels in Cardiovascular Function and Disease

2006 · Ryuji Inoue, Lars Jørn Jensen, et al. · Circulation Research · 367

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TRPM7, a novel regulator of actomyosin contractility and cell adhesion

2006 · Kristopher Clark, Michiel Langeslag, et al. · The EMBO Journal · 354

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Induction of epithelial–mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent

2013 · F M Davis, I Azimi, et al. · Oncogene · 333

TRPM7-Mediated Ca 2+ Signals Confer Fibrogenesis in Human Atrial Fibrillation

2010 · Jianyang Du, Jia Xie, et al. · Circulation Research · 331

Tissue-specific expression of TRP channel genes in the mouse and its variation in three different mouse strains

2006 · Christiane Kunert-Keil, Frederike Bisping, et al. · BMC Genomics · 330

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TRPM7 is essential for Mg2+ homeostasis in mammals

2010 · Lillia V. Ryazanova, Lusliany J. Rondon, et al. · Nature Communications · 321

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Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia

2009 · Hong-Shuo Sun, Michael F Jackson, et al. · Nature Neuroscience · 287

Functional expression of transient receptor potential melastatin- and vanilloid-related channels in pulmonary arterial and aortic smooth muscle

2006 · Xiao-Ru Yang, Mo-Jun Lin, et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 278

TRPM6 and TRPM7—Gatekeepers of human magnesium metabolism

2007 · Karl P. Schlingmann, Siegfried Waldegger, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 273

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Chanzyme TRPM7 Mediates the Ca2+ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation

2018 · Michael S. Schappe, Kalina Szteyn, et al. · Immunity · 252

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Works count: 2,022

Citation count: 58,210