Keyword

TRPM8

Description: TRPM8 is a transient receptor potential ion channel involved in sensory detection of cold and menthol, studied in neuroscience and physiology.

Primary topic: Ion Channels and Receptors (66%)

Related topic: Ion Channels and Receptors (66%)

OpenAlex ID: keywords/trpm8

ANKTM1, a TRP-like Channel Expressed in Nociceptive Neurons, Is Activated by Cold Temperatures

2003 · Gina M. Story, Andrea M. Peier, et al. · Cell · 2,486

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A TRP Channel that Senses Cold Stimuli and Menthol

2002 · Andrea M. Peier, Aziz Moqrich, et al. · Cell · 2,355

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Noxious Cold Ion Channel TRPA1 Is Activated by Pungent Compounds and Bradykinin

2004 · Michael Bandell, Gina M Story, et al. · Neuron · 1,827

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The menthol receptor TRPM8 is the principal detector of environmental cold

2007 · Diana M. Bautista, Jan Siemens, et al. · Nature · 1,388

TRP Channels and Pain

2013 · David Julius · Annual Review of Cell and Developmental Biology · 1,140

The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels

2004 · Thomas Voets, Guy Droogmans, et al. · Nature · 1,070

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Heat-Evoked Activation of the Ion Channel, TRPV4

2002 · Ali Deniz Güler, Hyosang Lee, et al. · Journal of Neuroscience · 1,031

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Effects of cannabinoids and cannabinoid‐enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes

2010 · Luciano De Petrocellis, Alessia Ligresti, et al. · British Journal of Pharmacology · 941

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TRPM8 Is Required for Cold Sensation in Mice

2007 · Ajay Dhaka, Amber N. Murray, et al. · Neuron · 930

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TRPV3 is a calcium-permeable temperature-sensitive cation channel

2002 · Haoxing Xu, I. Scott Ramsey, et al. · Nature · 920

Attenuated Cold Sensitivity in TRPM8 Null Mice

2007 · Raymond W. Colburn, Mary Lou Lubin, et al. · Neuron · 771

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Distinct expression of TRPM8, TRPA1, and TRPV1 mRNAs in rat primary afferent neurons with aδ/c‐fibers and colocalization with trk receptors

2005 · Kimiko Kobayashi, Tetsuo Fukuoka, et al. · The Journal of Comparative Neurology · 729

TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury

2005 · K. Obata · Journal of Clinical Investigation · 630

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PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain

2005 · Tibor Rohács, Coeli M B Lopes, et al. · Nature Neuroscience · 602

Distinct expression of TRPM8, TRPA1, and TRPV1 mRNAs in rat primary afferent neurons with Aδ/C-fibers and colocalization with Trk receptors

2007 · 希実子小林 · Medical Entomology and Zoology · 572

Cannabinoid Ligands Targeting TRP Channels

2019 · Chanté Muller, Paula Morales, et al. · Frontiers in Molecular Neuroscience · 568

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Bimodal Action of Menthol on the Transient Receptor Potential Channel TRPA1

2007 · Yuji Karashima, Nils Damann, et al. · Journal of Neuroscience · 521

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Thermosensation and pain

2004 · Makoto Tominaga, Michael J. Caterina · Journal of Neurobiology · 520

2-Aminoethoxydiphenyl Borate Is a Common Activator of TRPV1, TRPV2, and TRPV3

2004 · Hong-Zhen Hu, Qihai Gu, et al. · Journal of Biological Chemistry · 517

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Somatosensory neuron types identified by high-coverage single-cell RNA-sequencing and functional heterogeneity

2015 · Chang-Lin Li, Kai-Cheng Li, et al. · Cell Research · 460

Characterization of the mouse cold‐menthol receptor TRPM8 and vanilloid receptor type‐1 VR1 using a fluorometric imaging plate reader (FLIPR) assay

2004 · H‐J Behrendt, T Germann, et al. · British Journal of Pharmacology · 458

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Genome-wide association study reveals three susceptibility loci for common migraine in the general population

2011 · Daniel I Chasman, Markus Schürks, et al. · Nature Genetics · 432

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Analgesia Mediated by the TRPM8 Cold Receptor in Chronic Neuropathic Pain

2006 · Clare J. Proudfoot, Emer M. Garry, et al. · Current Biology · 419

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More than cool: Promiscuous relationships of menthol and other sensory compounds

2006 · Lindsey J. Macpherson, Sun Wook Hwang, et al. · Molecular and Cellular Neuroscience · 401

Clues to understanding cold sensation: Thermodynamics and electrophysiological analysis of the cold receptor TRPM8

2004 · Sebastian Brauchi, Patricio Orio, et al. · Proceedings of the National Academy of Sciences · 375

Works count: 3,166

Citation count: 94,870