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Keyword

tumor evolution

Description: The genetic and phenotypic changes in cancer cells and tumor populations over time, studied in cancer biology and oncology.
OpenAlex ID: keywords/tumor-evolution
Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
2012 · Marco Gerlinger, Andrew J. Rowan, et al. · New England Journal of Medicine · 7,753
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The cancer genome
2009 · Michael R. Stratton, Peter J. Campbell, et al. · Nature · 3,449
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Patterns of somatic mutation in human cancer genomes
2007 · Christopher Greenman, Philip Stephens, et al. · Nature · 3,081
Pan-cancer analysis of whole genomes
2020 · Lauri A. Aaltonen, Federico Abascal, et al. · Nature · 3,055
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Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
2017 · Nicholas McGranahan, Charles Swanton · Cell · 2,820
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Tumour evolution inferred by single-cell sequencing
2011 · Nicholas Navin, Jude Kendall, et al. · Nature · 2,595
Targeting apoptosis in cancer therapy
2020 · Benedito A. Carneiro, Wafik S. El-Deiry · Nature Reviews Clinical Oncology · 2,543
Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development
2011 · Philip J. Stephens, Chris D. Greenman, et al. · Cell · 2,419
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Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab
2017 · Nadeem Riaz, Jonathan J. Havel, et al. · Cell · 2,381
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Tracking the Evolution of Non–Small-Cell Lung Cancer
2017 · Mariam Jamal-Hanjani, Gareth A. Wilson, et al. · New England Journal of Medicine · 2,338
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The causes and consequences of genetic heterogeneity in cancer evolution
2013 · Rebecca A. Burrell, Nicholas McGranahan, et al. · Nature · 2,258
Evolution of the Cancer Stem Cell Model
2014 · Antonija Kreso, John E. Dick · Cell stem cell · 2,224
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Absolute quantification of somatic DNA alterations in human cancer
2012 · Scott L Carter, Kristian Cibulskis, et al. · Nature Biotechnology · 2,052
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Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
2017 · Christopher Abbosh, Nicolai J. Birkbak, et al. · Nature · 1,875
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Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
2013 · Andrea Sottoriva, Inmaculada Spiteri, et al. · Proceedings of the National Academy of Sciences · 1,737
Cancer as an evolutionary and ecological process
2006 · Lauren M.F. Merlo, John W. Pepper, et al. · Nature reviews. Cancer · 1,699
Tumor heterogeneity: Causes and consequences
2009 · Andriy Marusyk, Kornelia Polyak · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · 1,602
Small-cell lung cancer
2021 · Charles M. Rudin, Elisabeth Brambilla, et al. · Nature Reviews Disease Primers · 1,572
Current and future perspectives of liquid biopsies in genomics-driven oncology
2018 · Ellen Heitzer, Imran S. Haque, et al. · Nature Reviews Genetics · 1,539
Universal Patterns of Selection in Cancer and Somatic Tissues
2017 · Iñigo Martincorena, Keiran M. Raine, et al. · Cell · 1,515
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Evolutionary dynamics: exploring the equations of life
2007 · Choice Reviews Online · 1,486
Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution
2011 · Keiko Taguchi, Hozumi Motohashi, et al. · Genes to Cells · 1,473
Endogenous DNA Damage as a Source of Genomic Instability in Cancer
2017 · Anthony Tubbs, André Nussenzweig · Cell · 1,443
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The Life History of 21 Breast Cancers
2012 · Serena Nik-Zainal, Peter Van Loo, et al. · Cell · 1,442
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The evolutionary history of lethal metastatic prostate cancer
2015 · ICGC Prostate UK Group, Gunes Gundem, et al. · Nature · 1,388
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Works count: 11,680
Citation count: 309,800
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