Keyword

ULK1

Description: ULK1 is a protein kinase that regulates autophagy and cellular responses to nutrient availability in eukaryotic cells.

Primary topic: Autophagy in Disease and Therapy (48%)

OpenAlex ID: keywords/ulk1

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

2011 · Joungmok Kim, Mondira Kundu, et al. · Nature Cell Biology · 7,196

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

2015 · Michael Lazarou, Danielle A. Sliter, et al. · Nature · 2,760

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

2010 · Daniel F. Egan, David B. Shackelford, et al. · Science · 2,586

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

2009 · Nao Hosokawa, Taichi Hara, et al. · Molecular Biology of the Cell · 2,069

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

2009 · Chang Hwa Jung, Chang Bong Jun, et al. · Molecular Biology of the Cell · 2,020

Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

2011 · Haitao Wen, Denis Gris, et al. · Nature Immunology · 1,810

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ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase

2013 · Ryan C. Russell, Ye Tian, et al. · Nature Cell Biology · 1,577

ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

2009 · Ian G. Ganley, Du H. Lam, et al. · Journal of Biological Chemistry · 1,556

MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB

2012 · Jose A. Martina, Yong Chen, et al. · Autophagy · 1,367

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Discovery of Atg5/Atg7-independent alternative macroautophagy

2009 · Yuya Nishida, Satoko Arakawa, et al. · Nature · 1,102

The role of the Atg1/ULK1 complex in autophagy regulation

2010 · Noboru Mizushima · Current Opinion in Cell Biology · 1,063

FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

2008 · Taichi Hara, Akito Takamura, et al. · The Journal of Cell Biology · 975

Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins

2010 · Eisuke Itakura, Noboru Mizushima · Autophagy · 841

Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes

2006 · Andrew R. J. Young, Edmond Y. W. Chan, et al. · Journal of Cell Science · 814

The mammalian ULK1 complex and autophagy initiation

2017 · Maria Zachari, Ian G. Ganley · Essays in Biochemistry · 783

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mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6

2013 · Francesca Nazio, Flavie Strappazzon, et al. · Nature Cell Biology · 781

Autophagy regulation by nutrient signaling

2013 · Ryan C Russell, Hai-Xin Yuan, et al. · Cell Research · 710

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Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation

2010 · Hannah E.J. Polson, Jane de Lartigue, et al. · Autophagy · 709

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Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates

2015 · Daniel F. Egan, Matthew G.H. Chun, et al. · Molecular Cell · 708

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Cyclic Dinucleotides Trigger ULK1 (ATG1) Phosphorylation of STING to Prevent Sustained Innate Immune Signaling

2013 · Hiroyasu Konno, Keiko Konno, et al. · Cell · 675

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RETRACTED: Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

2011 · Jennifer Martinez, Johann Almendinger, et al. · Proceedings of the National Academy of Sciences · 654

Autophagy is a protective mechanism in normal cartilage, and its aging‐related loss is linked with cell death and osteoarthritis

2010 · Beatriz Caramés, Noboru Taniguchi, et al. · Arthritis & Rheumatism · 630

The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR

2011 · Dan Egan, Joungmok Kim, et al. · Autophagy · 627

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ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy

2014 · Wenxian Wu, Weili Tian, et al. · EMBO Reports · 584

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Dynamic and transient interactions of Atg9 with autophagosomes, but not membrane integration, are required for autophagy

2012 · A. Orsi, M. Razi, et al. · Molecular Biology of the Cell · 581

Works count: 2,697

Citation count: 110,000