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Keyword

uPAR

Description: The urokinase plasminogen activator receptor, a cell-surface protein involved in plasminogen activation, extracellular matrix remodeling, and signaling.
Wikidata ID: wiki/Q7900869
OpenAlex ID: keywords/upar
uPAR: a versatile signalling orchestrator
2002 · Francesco Blasi, Peter Carmeliet · Nature Reviews Molecular Cell Biology · 1,226
Regulation of cell signalling by uPAR
2009 · Harvey W. Smith, Chris J. Marshall · Nature Reviews Molecular Cell Biology · 962
The plasminogen activation system in tumor growth, invasion, and metastasis
2000 · P. A. Andreasen, R. Egelund, et al. · Cellular and Molecular Life Sciences · 944
FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3–CCL2 Signaling
2016 · Xuguang Yang, Yuli Lin, et al. · Cancer Research · 742
Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis.
1990 · A.L. Roldan, M.V. Cubellis, et al. · The EMBO Journal · 603
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Cellular receptor for urokinase plasminogen activator. Carboxyl-terminal processing and membrane anchoring by glycosyl-phosphatidylinositol
1991 · M Ploug, E Rønne, et al. · Journal of Biological Chemistry · 574
Multifaceted Role of the Urokinase-Type Plasminogen Activator (uPA) and Its Receptor (uPAR): Diagnostic, Prognostic, and Therapeutic Applications
2018 · Niaz Mahmood, Catalin Mihalcioiu, et al. · Frontiers in Oncology · 479
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Amoeboid shape change and contact guidance: T-lymphocyte crawling through fibrillar collagen is independent of matrix remodeling by MMPs and other proteases
2003 · Katarina Wolf, Regina Müller, et al. · Blood · 442
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A Reexamination of Active and Passive Tumor Targeting by Using Rod-Shaped Gold Nanocrystals and Covalently Conjugated Peptide Ligands
2010 · Xiaohua Huang, Xianghong Peng, et al. · ACS Nano · 427
Evolving role of uPA/uPAR system in human cancers
2008 · Kathleen Dass, Aamir Ahmad, et al. · Cancer Treatment Reviews · 423
Hypoxia-driven selection of the metastatic phenotype
2007 · Richard Sullivan, Charles H. Graham · Cancer and Metastasis Reviews · 410
ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility
2003 · Emmanuel Vial, Erik Sahai, et al. · Cancer Cell · 406
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The Urokinase Plasminogen Activator System: Role in Malignancy
2004 · Michael Duffy · Current Pharmaceutical Design · 401
Coagulation, fibrinolysis, and fibrin deposition in acute lung injury
2003 · Steven Idell · Critical Care Medicine · 381
The urokinase plasminogen activator system in cancer: Recent advances and implication for prognosis and therapy
2003 · Nicolai Sidenius, Francesco Blasi · Cancer and Metastasis Reviews · 368
The plasminogen activator system: biology and regulation
1999 · J. P. Irigoyen, P. Muñoz-Cánoves, et al. · Cellular and Molecular Life Sciences · 368
CD44v6 Dependence of Premetastatic Niche Preparation by Exosomes
2009 · Thorsten Jung, Donatello Castellana, et al. · Neoplasia · 345
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Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling
2017 · Min Liu, Kaili Liang, et al. · Nature Communications · 343
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Human hepatocellular carcinomas with “Stemness”-related marker expression: keratin 19 expression and a poor prognosis
2011 · Haeryoung Kim, Gi Hong Choi, et al. · Hepatology · 341
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β-Catenin—A Linchpin in Colorectal Carcinogenesis?
2002 · Newton Alexander Chiang Shuek Wong, Massimo Pignatelli · American Journal Of Pathology · 341
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Myosin Light Chain Kinase Functions Downstream of Ras/ERK to Promote Migration of Urokinase-Type Plasminogen Activator-Stimulated Cells in an Integrin-Selective Manner
1999 · Diem H.D. Nguyen, Andrew D. Catling, et al. · The Journal of Cell Biology · 312
uPA and uPAR in fibrinolysis, immunity and pathology
2004 · Anna Mondino, Francesco Blasi · Trends in Immunology · 309
Plasminogen activator inhibitor-1 detaches cells from extracellular matrices by inactivating integrins
2003 · Ralf-Peter Czekay, Kathleen Aertgeerts, et al. · The Journal of Cell Biology · 304
LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration
2018 · Mi Deng, Xun Gui, et al. · Nature · 303
The urokinase receptor is required for human monocyte chemotaxis in vitro.
1994 · M R Gyetko, R F Todd, et al. · Journal of Clinical Investigation · 298
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Works count: 3,159
Citation count: 73,780
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