Product
Help
Pricing
About
Jobs
Log in
Get started
Keyword
Add to collection
urantide
Description:
A synthetic peptide antagonist of the urotensin-II receptor studied in pharmacology and cardiovascular disease research.
Primary topic:
Cardiovascular, Neuropeptides, and Oxidative Stress Research (45%)
Related topic:
Cardiovascular, Neuropeptides, and Oxidative Stress Research (45%)
OpenAlex ID:
keywords/urantide
Urantide: an ultrapotent urotensin II antagonist peptide in the rat aorta
2003
·
Riccardo Patacchini
, Paolo Santicioli
, et al.
·
British Journal of Pharmacology
·
106
PDF
Urotensin II and renal function in the rat
2006
·
W. Song
, A.E.S. Abdel-Razik
, et al.
·
Kidney International
·
77
Urantide mimics urotensin-II induced calcium release in cells expressing recombinant UT receptors
2004
·
Valeria Camarda
, Wei Song
, et al.
·
European Journal of Pharmacology
·
63
EGFR trans-activation by urotensin II receptor is mediated by β-arrestin recruitment and confers cardioprotection in pressure overload-induced cardiac hypertrophy
2011
·
Giovanni Esposito
, Cinzia Perrino
, et al.
·
Basic Research in Cardiology
·
60
Biased signaling regulates the pleiotropic effects of the urotensin II receptor to modulate its cellular behaviors
2014
·
Cédric Brulé
, Nicolas Perzo
, et al.
·
The FASEB Journal
·
51
Renal and vascular actions of urotensin II
2006
·
N. Ashton
·
Kidney International
·
50
Inhibition of UII/UTR System Relieves Acute Inflammation of Liver through Preventing Activation of NF-κB Pathway in ALF Mice
2013
·
Dong-yu Liang
, Liang-ming Liu
, et al.
·
PLoS ONE
·
43
PDF
The UII/UT System Mediates Upregulation of Proinflammatory Cytokines through p38 MAPK and NF-κB Pathways in LPS-Stimulated Kupffer Cells
2015
·
Liang Ming Liu
, Dong Yu Liang
, et al.
·
PLoS ONE
·
42
PDF
Urotensin receptors as a new target for CLP induced septic lung injury in mice
2018
·
Elif Cadirci
, Rustem Anil Ugan
, et al.
·
Naunyn-Schmiedeberg s Archives of Pharmacology
·
41
Potent cardiovascular effects of homologous urotensin II (UII)-related peptide and UII in unanesthetized eels after peripheral and central injections
2010
·
Shigenori Nobata
, John A. Donald
, et al.
·
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
·
39
Role of PKC in the novel synergistic action of urotensin II and angiotensin II and in urotensin II-induced vasoconstriction
2006
·
Yan-Xia Wang
, Ying-Jiong Ding
, et al.
·
American Journal of Physiology-Heart and Circulatory Physiology
·
38
Urotensin II receptor predicts the clinical outcome of prostate cancer patients and is involved in the regulation of motility of prostate adenocarcinoma cells
2010
·
Paolo Grieco
, Renato Franco
, et al.
·
Journal of Cellular Biochemistry
·
37
Urotensin II induction of adult cardiomyocytes hypertrophy involves the Akt/GSK-3β signaling pathway
2010
·
D. Gruson
, A. Ginion
, et al.
·
Peptides
·
37
The peptidic urotensin‐II receptor ligand GSK248451 possesses less intrinsic activity than the low‐efficacy partial agonists SB‐710411 and urantide in native mammalian tissues and recombinant cell systems
2006
·
David J Behm
, Gerald Stankus
, et al.
·
British Journal of Pharmacology
·
37
PDF
In vitro and in vivo pharmacological characterization of the novel UT receptor ligand [Pen5, D Trp7,Dab8]urotensin II(4–11) (UFP‐803)
2005
·
Valeria Camarda
, Martina Spagnol
, et al.
·
British Journal of Pharmacology
·
34
Urotensin II prevents cardiomyocyte apoptosis induced by doxorubicin via Akt and ERK
2012
·
Yen-Ling Chen
, Shih-Hurng Loh
, et al.
·
European Journal of Pharmacology
·
33
The involvement of transforming growth factor-β1 secretion in Urotensin II-induced collagen synthesis in neonatal cardiac fibroblasts
2006
·
Hong-Yan Dai
, Wei-Qiang Kang
, et al.
·
Regulatory Peptides
·
32
Urotensin II receptor determines prognosis of bladder cancer regulating cell motility/invasion
2014
·
Renato Franco
, Silvia Zappavigna
, et al.
·
Journal of Experimental & Clinical Cancer Research
·
29
PDF
Urotensin‐ II receptor is over‐expressed in colon cancer cell lines and in colon carcinoma in humans
2013
·
Alessandro Federico
, Silvia Zappavigna
, et al.
·
European Journal of Clinical Investigation
·
27
Lead Optimization of P5U and Urantide: Discovery of Novel Potent Ligands at the Urotensin-II Receptor
2014
·
Alfonso Carotenuto
, Luigia Auriemma
, et al.
·
Journal of Medicinal Chemistry
·
26
New Insight into the Binding Mode of Peptide Ligands at Urotensin-II Receptor: Structure−Activity Relationships Study on P5U and Urantide
2009
·
Paolo Grieco
, Alfonso Carotenuto
, et al.
·
Journal of Medicinal Chemistry
·
26
Cell and tissue responses of a range of Urotensin II analogs at cloned and native urotensin II receptors. Evidence for coupling promiscuity
2006
·
Wei Song
, John McDonald
, et al.
·
Naunyn-Schmiedeberg s Archives of Pharmacology
·
26
Urotensin-II Receptor Ligands. From Agonist to Antagonist Activity
2005
·
Paolo Grieco
, Alfonso Carotenuto
, et al.
·
Journal of Medicinal Chemistry
·
25
The urotensin II receptor antagonist, urantide, protects against atherosclerosis in rats
2013
·
JUAN ZHAO
, QUAN-XIN YU
, et al.
·
Experimental and Therapeutic Medicine
·
23
PDF
Characterization of Urotensin-II Receptor Structural Domains Involved in the Recognition of U-II, URP, and Urantide
2006
·
Stéphane Boivin
, Laure Guilhaudis
, et al.
·
Biochemistry
·
22
Show more works
View as search
Works count:
143
Citation count:
1,681
Year
Topic
Type
