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Keyword

WTAP

Description: WTAP is a protein-coding gene that encodes a component of the mRNA N6-methyladenosine methyltransferase complex, involved in RNA modification and gene regulation.
Wikidata ID: wiki/Q18974072
OpenAlex ID: keywords/wtap
A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation
2013 · Jianzhao Liu, Yanan Yue, et al. · Nature Chemical Biology · 3,410
Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase
2014 · Xiao-Li Ping, Bao-Fa Sun, et al. · Cell Research · 2,358
m6A RNA methylation promotes XIST-mediated transcriptional repression
2016 · Deepak P. Patil, Chun-Kan Chen, et al. · Nature · 1,737
Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites
2014 · Schraga Schwartz, Maxwell R. Mumbach, et al. · Cell Reports · 1,217
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The role of m6A RNA methylation in human cancer
2019 · Xiao-Yu Chen, Jing Zhang, et al. · Molecular Cancer · 1,069
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VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation
2018 · Yanan Yue, Jun Liu, et al. · Cell Discovery · 956
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Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal
2018 · Jing Wen, Ruitu Lv, et al. · Molecular Cell · 943
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RNA N6-methyladenosine modification in cancers: current status and perspectives
2018 · Xiaolan Deng, Rui Su, et al. · Cell Research · 845
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WTAP facilitates progression of hepatocellular carcinoma via m6A-HuR-dependent epigenetic silencing of ETS1
2019 · Yunhao Chen, Chuanhui Peng, et al. · Molecular Cancer · 630
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Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m 6 A machinery component Wtap/Fl(2)d
2018 · Philip Knuckles, Tina Lence, et al. · Genes & Development · 582
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Interactions, localization, and phosphorylation of the m6A generating METTL3–METTL14–WTAP complex
2018 · Eva Schöller, Franziska Weichmann, et al. · RNA · 433
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Identification of Wilms' Tumor 1-associating Protein Complex and Its Role in Alternative Splicing and the Cell Cycle
2013 · Keiko Horiuchi, Takeshi Kawamura, et al. · Journal of Biological Chemistry · 354
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Exosome-derived circCCAR1 promotes CD8 + T-cell dysfunction and anti-PD1 resistance in hepatocellular carcinoma
2023 · Zongqiang Hu, Gang Chen, et al. · Molecular Cancer · 329
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SUMOylation of the m6A-RNA methyltransferase METTL3 modulates its function
2018 · Yuzhang Du, Guofang Hou, et al. · Nucleic Acids Research · 313
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m6A RNA methylation regulates the fate of endogenous retroviruses
2021 · Tomasz Chelmicki, Emeline Roger, et al. · Nature · 295
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A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing
2015 · Benoit Moindrot, Andrea Cerase, et al. · Cell Reports · 266
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RNA m6A methylation participates in regulation of postnatal development of the mouse cerebellum
2018 · Chunhui Ma, Mengqi Chang, et al. · Genome biology · 252
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Epigenetic Regulation of m6A Modifications in Human Cancer
2019 · Wei Zhao, Xiaoqian Qi, et al. · Molecular Therapy — Nucleic Acids · 249
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Glucose Is Involved in the Dynamic Regulation of m6A in Patients With Type 2 Diabetes
2018 · Ying Yang, Fan Shen, et al. · The Journal of Clinical Endocrinology & Metabolism · 245
WTAP is a novel oncogenic protein in acute myeloid leukemia
2014 · H Bansal, Q Yihua, et al. · Leukemia · 243
Identification of WTAP, a novel Wilms' tumour 1-associating protein
2000 · N. A. Little, N. D. Hastie, et al. · Human Molecular Genetics · 218
mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
2021 · Elodie Villa, Umakant Sahu, et al. · Molecular Cell · 187
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piRNA-30473 contributes to tumorigenesis and poor prognosis by regulating m6A RNA methylation in DLBCL
2020 · Huiying Han, Gao Fan, et al. · Blood · 180
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Wilms’ tumor 1-associating protein promotes renal cell carcinoma proliferation by regulating CDK2 mRNA stability
2018 · Jingyuan Tang, Feng Wang, et al. · Journal of Experimental & Clinical Cancer Research · 178
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Circ0008399 Interaction with WTAP Promotes Assembly and Activity of the m6A Methyltransferase Complex and Promotes Cisplatin Resistance in Bladder Cancer
2021 · Wenjie Wei, Jiayin Sun, et al. · Cancer Research · 177
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Works count: 1,011
Citation count: 31,340
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