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Keyword

YTHDF2

Description: A human protein encoded by the YTHDF2 gene that recognizes N6-methyladenosine-modified RNA and regulates its stability.
Wikidata ID: wiki/Q18040291
OpenAlex ID: keywords/ythdf2
N6-methyladenosine-dependent regulation of messenger RNA stability
2013 · Xiao Wang, Zhike Lu, et al. · Nature · 4,539
N6-methyladenosine Modulates Messenger RNA Translation Efficiency
2015 · Xiao Wang, Boxuan Simen Zhao, et al. · Cell · 3,467
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N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions
2015 · Nian Liu, Qing Dai, et al. · Nature · 1,981
YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA
2017 · Hailing Shi, Xiao Wang, et al. · Cell Research · 1,807
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YTHDF2 destabilizes m6A-containing RNA through direct recruitment of the CCR4–NOT deadenylase complex
2016 · Hao Du, Ya Zhao, et al. · Nature Communications · 1,467
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RNA N6‐methyladenosine methyltransferase‐like 3 promotes liver cancer progression through YTHDF2‐dependent posttranscriptional silencing of SOCS2
2017 · Mengnuo Chen, Lai Wei, et al. · Hepatology · 1,376
Dynamic m6A mRNA methylation directs translational control of heat shock response
2015 · Jun Zhou, Ji Wan, et al. · Nature · 1,236
Histone lactylation drives oncogenesis by facilitating m6A reader protein YTHDF2 expression in ocular melanoma
2021 · Jie Yu, Peiwei Chai, et al. · Genome biology · 941
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m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade
2019 · Seungwon Yang, Jiangbo Wei, et al. · Nature Communications · 743
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m6A enhances the phase separation potential of mRNA
2019 · Ryan J. Ries, Sara Zaccara, et al. · Nature · 702
m6A modulates haematopoietic stem and progenitor cell specification
2017 · Chunxia Zhang, Yusheng Chen, et al. · Nature · 582
N6-Methyladenosine Modification Controls Circular RNA Immunity
2019 · Y. Grace Chen, Robert Chen, et al. · Molecular Cell · 571
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Endoribonucleolytic Cleavage of m6A-Containing RNAs by RNase P/MRP Complex
2019 · Ok Hyun Park, Hongseok Ha, et al. · Molecular Cell · 571
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m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition
2017 · Boxuan Simen Zhao, Xiao Wang, et al. · Nature · 565
METTL14 suppresses proliferation and metastasis of colorectal cancer by down-regulating oncogenic long non-coding RNA XIST
2020 · Xiao Yang, Sen Zhang, et al. · Molecular Cancer · 513
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Targeting the RNA m6A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia
2019 · Jasmin Paris, Marcos Morgan, et al. · Cell stem cell · 504
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m6A modification controls the innate immune response to infection by targeting type I interferons
2018 · Roni Winkler, Ella Gillis, et al. · Nature Immunology · 456
Molecular Mechanisms Driving mRNA Degradation by m6A Modification
2020 · Yujin Lee, Junho Choe, et al. · Trends in Genetics · 450
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Genome-Wide Maps of m6A circRNAs Identify Widespread and Cell-Type-Specific Methylation Patterns that Are Distinct from mRNAs
2017 · Chan Zhou, Benoit Molinie, et al. · Cell Reports · 429
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The RNA m6A Reader YTHDF2 Maintains Oncogene Expression and Is a Targetable Dependency in Glioblastoma Stem Cells
2020 · Deobrat Dixit, Briana C. Prager, et al. · Cancer Discovery · 411
m6A RNA methyltransferases METTL3/14 regulate immune responses to anti‐PD‐1 therapy
2020 · Lingling Wang, Hui Hui, et al. · The EMBO Journal · 408
METTL14-mediated N6-methyladenosine modification of SOX4 mRNA inhibits tumor metastasis in colorectal cancer
2020 · Xiaoxiang Chen, Mu Xu, et al. · Molecular Cancer · 407
RNA demethylase ALKBH5 prevents pancreatic cancer progression by posttranscriptional activation of PER1 in an m6A-YTHDF2-dependent manner
2020 · Xingya Guo, Kai Li, et al. · Molecular Cancer · 398
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YTHDF2 promotes the liver cancer stem cell phenotype and cancer metastasis by regulating OCT4 expression via m6A RNA methylation
2020 · Chuanzhao Zhang, Shanzhou Huang, et al. · Oncogene · 393
The RNA m 6 A Reader YTHDF2 Is Essential for the Post-transcriptional Regulation of the Maternal Transcriptome and Oocyte Competence
2017 · Ivayla Ivanova, Christian Much, et al. · Molecular Cell · 393
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Works count: 1,911
Citation count: 62,760
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