Keyword

zerumbone

Description: Zerumbone is a naturally occurring sesquiterpene compound found in ginger plants and studied for its biological and pharmacological effects.

Primary topic: Ginger and Zingiberaceae research (50%)

Wikidata ID: wiki/Q27132897

OpenAlex ID: keywords/zerumbone

Cancer prevention and therapy through the modulation of the tumor microenvironment

2015 · Stephanie C. Casey, Amedeo Amedei, et al. · Seminars in Cancer Biology · 374

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Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation accompanied by apoptosis: the alpha,beta-unsaturated carbonyl group is a prerequisite

2002 · A. Murakami · Carcinogenesis · 302

Potential of Spice-Derived Phytochemicals for Cancer Prevention

2008 · Bharat Aggarwal, Ajaikumar Kunnumakkara, et al. · Planta Medica · 269

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Targeting Histone Deacetylases with Natural and Synthetic Agents: An Emerging Anticancer Strategy

2018 · Amit Kumar Singh, Anupam Bishayee, et al. · Nutrients · 221

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Zerumbone abolishes NF-κB and IκBα kinase activation leading to suppression of antiapoptotic and metastatic gene expression, upregulation of apoptosis, and downregulation of invasion

2005 · Yasunari Takada, Akira Murakami, et al. · Oncogene · 196

Zerumbone Enhances TRAIL-Induced Apoptosis through the Induction of Death Receptors in Human Colon Cancer Cells: Evidence for an Essential Role of Reactive Oxygen Species

2009 · Supachai Yodkeeree, Bokyung Sung, et al. · Cancer Research · 181

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Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes

2004 · Yoshimasa Nakamura, Chiho Yoshida, et al. · FEBS Letters · 180

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Zingiber zerumbet (L.) Smith: A Review of Its Ethnomedicinal, Chemical, and Pharmacological Uses

2011 · N. J. Yob, S. Mohd. Jofrry, et al. · Evidence-based Complementary and Alternative Medicine · 175

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Green Synthesis of Zinc Oxide Nanoparticles for Enhanced Adsorption of Lead Ions from Aqueous Solutions: Equilibrium, Kinetic and Thermodynamic Studies

2017 · Susan Azizi, Mahnaz Mahdavi Shahri, et al. · Molecules · 171

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Zerumbone-loaded nanostructured lipid carriers: preparation, characterization, and antileukemic effect

2013 · Heshu Rahman, Abdullah Rasedee, et al. · International Journal of Nanomedicine · 169

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Zerumbone, a tropical ginger sesquiterpene, inhibits colon and lung carcinogenesis in mice

2008 · Mihye Kim, Shingo Miyamoto, et al. · International Journal of Cancer · 168

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Zerumbone, a sesquiterpene in subtropical ginger, suppresses skin tumor initiation and promotion stages in ICR mice

2004 · Akira Murakami, Takuji Tanaka, et al. · International Journal of Cancer · 167

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Potential of Zerumbone as an Anti-Cancer Agent

2019 · Sosmitha Girisa, Bano Shabnam, et al. · Molecules · 161

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Zerumbone induced apoptosis in liver cancer cells via modulation of Bax/Bcl-2 ratio

2007 · SA Sharifah Sakinah, S Tri Handayani, et al. · Cancer Cell International · 152

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Cytotoxic components of Zingiber zerumbet, Curcuma zedoaria and C. domestica

1980 · H.W.D. Matthes, B. Luu, et al. · Phytochemistry · 152

Naturally occurring immunomodulators with antitumor activity: An insight on their mechanisms of action

2017 · Shimaa Ibrahim Abdelmonym Mohamed, Ibrahim Jantan, et al. · International Immunopharmacology · 140

In Vitro Ultramorphological Assessment of Apoptosis Induced by Zerumbone on (HeLa )

2009 · Siddig Ibrahim Abdel Wahab, Ahmad Bustamam Abdul, et al. · BioMed Research International · 138

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Zerumbone Down-regulates Chemokine Receptor CXCR4 Expression Leading to Inhibition of CXCL12-Induced Invasion of Breast and Pancreatic Tumor Cells

2008 · Bokyung Sung, Sonia Jhurani, et al. · Cancer Research · 135

Key cell signaling pathways modulated by zerumbone: Role in the prevention and treatment of cancer

2012 · Remya Prasannan, Karunakaran A. Kalesh, et al. · Biochemical Pharmacology · 134

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Antitumor Activity of Extract of Zingiber aromaticum and Its Bioactive Sesquiterpenoid Zerumbone

2003 · Chandra Kirana, Graeme H. McIntosh, et al. · Nutrition and Cancer · 133

Naturally Occurring Small‐Molecule Inhibitors of Hedgehog/GLI‐Mediated Transcription

2008 · Takahiro Hosoya, Midori A. Arai, et al. · ChemBioChem · 129

Suppression of dextran sodium sulfate-induced colitis in mice by zerumbone, a subtropical ginger sesquiterpene, and nimesulide: separately and in combination

2003 · Akira Murakami, Ryohei Hayashi, et al. · Biochemical Pharmacology · 128

Characterization of the inclusion complex of zerumbone with hydroxypropyl-β-cyclodextrin

2010 · Eltayeb E.M. Eid, Ahmad Bustamam Abdul, et al. · Carbohydrate Polymers · 127

Identification of Zerumbone inZingiber zerumbetSmith as a Potent Inhibitor of 12-O-Tetradecanoylphorbol-13-acetate-induced Epstein-Barr Virus Activation

1999 · Akira MURAKAMI, Miyuki TAKAHASHI, et al. · Bioscience Biotechnology and Biochemistry · 124

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Anti-inflammatory effect of zerumbone on acute and chronic inflammation models in mice

2010 · M.R. Sulaiman, E.K. Perimal, et al. · Fitoterapia · 123

Works count: 1,038

Citation count: 17,280