Understanding Cholesterol Synthesis and Absorption Is the Key to Achieving Cholesterol Targets
Year: 2007
Type: article
Abstract: The importance of plasma cholesterol reduction in the attenuation of cardiovascular (CV) risk has been clearly demonstrated in large clinical trials using statins.However, despite the clear risks of hyperlipidaemia and the proven benefits of lipid-lowering therapies, only a minority of patients currently achieve recommended low-density lipoprotein (LDL) cholesterol treatment goals in clinical practice.1,2 More patients are being treated for lipid reduction than ever before, but there remains a substantial degree of undertreatment.This is due to a number of factors, including patient non-compliance, tolerability issues, variable physician follow-up, patients not receiving adequate dosages of the lipid-lowering drugs available and the drugs themselves not being optimal.Statins are widely prescribed and are established as first-line therapy for the primary and secondary prevention of coronary artery disease.
Source: Asia Pacific Cardiology
Author: Karam M Kostner
Institution: Princess Alexandra Hospital
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W115285690