Sensitization of guinea-pigs to measles vaccines.
Year: 1969
Type: article
Abstract: Attenuated measles virus vaccine of chick embryo tissue culture origin and unadsorbed inactivated measles vaccines derived from monkey kidney tissue culture produced little or no sensitization of guinea-pigs, as monitored by the Schultz–Dale or passive cutaneous anaphylaxis techniques. Inactivated vaccines of both monkey kidney and chick embryo tissue culture origins were sensitizing when they contained a mineral adjuvant. The sensitizing activity was also present in the aqueous phase of Tween 80–ether-treated measles virus fluid and in uninfected tissue cultures of simian, avian and human origins.
Source: PubMed Central
Authors: M A Aprile, D Kadar, S Wilson
Language: English
Topic: Virology and Viral Diseases
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W115348553