Dehydrooligopeptides. V. Synthesis of N-carboxy .ALPHA.-dehydroamino acid anhydrides and their transformation to .ALPHA.-dehydroamino acid and dehydrooligopeptide derivatives.
Year: 1984
Type: article
Abstract: The synthesis of N-carboxy α-dehydroamino acid anhydrides (ΔNCA) from benzyloxycarbonyl-α-dehydroamino acids and the subsequent conversion of these products into new α-dehydroamino acid and dehydrooligopeptide derivatives are described. It was found that the new ΔNCA derivatives were very useful synthons for dehydropeptides. The racemization behavior and configurational determination of all the new dehydrooligopeptides thus obtained are discussed.
DOI: 10.1248/cpb.32.3934
Institution: Kanagawa University
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W1486524601
