Synthesis, characterization and antibacterial activity of imidazole derivatives of 1,10-phenanthroline and their Cu(II), Co(II) and Ni(II) complexes
Year: 2013
Type: article
Abstract: Six new CuL1 (L-1 = 4-bromo-2-(1H-imidazo[4,5-f][1,10]phenanthroline-2-yl)phenol), CoL1, NiL1, CuL2 (L-2 = 2-(1H-imidazo[4,5-f] [1,10]phenanthroline-2-yl)-5-methoxyphenol), CoL2 and NiL2 complexes were synthesized. L-1 and L-2 ligands were prepared by the condensation of 1,10-phenanthroline-5,6-dione with 5-bromosalicylaldehyde and 2-hydroxy-4-methoxybenzaldehyde, respectively. The structures of the compounds were determined by elemental analyses, IR, UV-visible, H-1-NMR, TGA, magnetic susceptibilities and molar conductance measurements. It is observed that the synthesized complexes have tetragonal and distorted square pyramidal geometrical structures. Antibacterial activity of the ligands and their metal complexes were tested against selected bacteria by disc diffusion method.
Authors: Mesut Gömleksiz, Belgin Erdem, Cihan Alkan
Institutions: Ahi Evran University, Fırat University
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W1496033285