Severe chronic active giftein‐Barr virus infection accompanied by virus‐associated hemophagocytic syndrome, cerebellar ataxia and encephalitis
Year: 1998
Type: article
Study design: Case Report
Abstract: We present a rare case of chronic active Epstein-Barr virus (EBV) infection showing various clinical outcomes. A 26-year-old man was admitted to our hospital due to persistent fever and dyspnea. Serologic response of the patient to EBV indicated chronic active infection. He showed pleuritis, parotitis, chronic hepatic dysfunction, disseminated intravascular coagulation, virus associated hemophaghocytic syndrome, acute rhabdomyolysis, acute renal failure, acute cerebellar ataxia, encephalitis and multiple brain abscesses. None of acyclovir, gancyclovir, prednisolone or interleukin-2 was effectual to abolish those abnormalities. This is the first report of transient cerebellar ataxia which aggravated to panencephalitis associated with chronic EBV infection.
Authors: SHU‐ICHI YAMASHITA, CHISA MURAKAMI, YOICHIRO IZUMI, HITOSHI SAWADA, YOSHIHIRO YAMAZAKI, TADA‐AKI YOKOTA, NOBUHIRO MATSUMOTO, SHIGERU MATSUKURA
Institutions: Kokura Memorial Hospital, University of Miyazaki
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W1497727675