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Primary anaplastic large cell lymphoma of central nervous system--a case report.

Year: 2005

Type: article

Abstract: Central nervous system (CNS) involvement is extremely rare in anaplastic large cell lymphoma (ALCL). Primary ALCL of CNS on radiology is often misdiagnosed as tuberculosis. We report a fatal case of primary ALCL of CNS in a 17 year old male. He came with history of headache and left partial seizures. MRI showed a well- circumscribed lesion in the right fronto-parietal lobe eroding the skull bone. Biopsy showed large pleomorphic cells. Immunohistochemical stains showed positivity for CD30, CD43, EMA and ALK-1. In spite of radiotherapy and steroids, patient expired. Hence a high level of suspicion is essential for early diagnosis and for instituting appropriate treatment.

Source: PubMed

Authors: A Rupani, C Modi, S Desai, J Rege

Institutions: Topiwala National Medical College & BYL Nair Charitable Hospital, Tata Memorial Hospital

Language: English

Topic: CNS Lymphoma Diagnosis and Treatment

Subfield: Clinical Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W1498136376

FWCI: 0.855

Cites:

Cited by: 27

Related to: 10