A Comparative Analysis of In-hospital Left Ventricular Function in Patients With Successful or Unsuccessful Streptokinase Thrombolysis Following Acute Myocardial Infarction
Year: 2012
Type: article
Study design: Observational Study
Abstract: Objective: To compare in-hospital left ventricular function in patients with unsuccessful and successfulthrombolysis presenting with acute myocardial infarction treated with streptokinase. Methodology: This comparative study was conducted at department of Cardiology, Lady Reading HospitalPeshawar, from October 2006 to October 2007. Two hundred patients with first acute myocardial infarctionwere divided into two groups: group A (successful thrombolysis) and group B (unsuccessful thrombolysis),using ECG criteria. To determine Left Ventricular Function, 2-D Echo was used. Results: Group A included 136 (68%) patients and group B included 64 (32%) patients. Impaired leftventricular function was found in 41 (30.1%) patients in group A and 41 (64.1%) patients in group B (p<0.001). Left ventricular failure was present in 31 (22.8%) patients of group A and 30 (46.9%) patients ofgroup B (p=0.001). Cardiogenic shock was diagnosed in 2 (1.5%) patients in group A and 6 (9.4%)patients in group B (p=0.008). Conclusion: Presence of LVF is strongly associated with unsuccessful thrombolytic therapy in this groupof patients.
Authors: Sher Bahadar Khan, Rafiullah, Hafiz Ur Rehman, Tariq Nawaz, Syed Tahir Shah, Syed Sadiq Shah, Hameedullah, Abdul Hadi, Muhammad Hafizullah, Adnan Mahmood Gul, Hikmatullah Jan, Syed Farhat Abbas Shah
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W1503143151