Andean high sensitivity to inflammation and hypertension
Year: 2006
Type: article
Abstract: "Low-degree inflammation is defined by increased concentrations of proinflammatory substances like tumoral necrosis factor alpha, interleukine 6 and C -reactive protein. Higher concentrations of these substances have been associated with increased risk of cardiovascuIar diseases, diabetes. hypertension and pregnancy induced hypertension. Abdominal obesity has been proposed as the alteration that originates the proinflammatory state. There are data suggesting and increased predisposition of Andean population to this pro-inflammatory state associated to lower degrees of visceral obesity, which could explain the higher risk of cardiovascular diseases¿ rnorbidity and mortality observed in the Last years in our population. The causes of the higher sensitivity probably are related to social, economic and demographic factors that differentiate developing from developed countries. Moreover, the access to health services and the prevalence of infectious diseases could be participating. In the present review, we present results supporting the theory of the social-economic-pathy, which include environmental factors as the primary cause that iscontributing to the high risk of cardiovascular diseases in the Andean region."
Language: Spanish
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W1503782986