Work

Radical Scavenging Capacity of Piper arboreum and Piper tuberculatum (Piperaceae)

Year: 2008

Type: article

Abstract: In the scope of our ongoing researchers on antioxidant compounds, twenty four extracts and fractions obtained from Piper arboreum Aublet and Piper tuberculatum Jacq. (Piperaceae) were screened for radical scavenging capacity (RSC) by using DPPH colorimetric assay. The strongest activity was found in ethyl acetate fractions from the leaves of P. arboreum (IC50 = 5.70 μg/mL) and P. tuberculatum (IC50 = 8.40 μg/mL). Hydromethanol fractions of the leaves of P. tuberculatum and P. arboreum showed moderate RSC, with values of IC50 (μg/mL) of 11.9 and 19.2, respectively. Additionally, a brief phytochemical study of the ethyl acetate fraction of P. arboreum leaves affording quercetin (1) and quercitrin (2), two flavonols with antioxidant activity previously described in the literature.

Source: LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)

Authors: Luís Octávio Regasini, Fernando Cotinguiba, Janaina R. Siqueira, Vanderlan da Silva Bolzani, Dulce Helena Siqueira Silva, Maysa Furlan, Massuo J. Kato

Language: English

Topic: Piperaceae Chemical and Biological Studies

Subfield: Pharmacology

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

Open Access status: green

Funders: Fundação de Amparo à Pesquisa do Estado de São Paulo, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

OpenAlex ID: W1542801166

FWCI: 0.625

Cites: 2

Cited by: 15

Related to: 10