Prevalence of plasmid-mediated quinolone resistance in Norwegian and Swedish clinical isolates of Escherchia coli and Klebsiella spp.
Year: 2008
Type: dissertation
Abstract: The aim of this study was to examine the presence of plasmid-mediated qnr and aac(6')-Ib-cr resistance genes among Escherichia coli and Klebsiella spp. clinical isolates obtained between 2003 and 2005 from Norway and Sweden and showed resistance and/or reduced susceptibility to nalidixic acid and ciprofloxacin, respectively. Prevalence of the qnr (1.6%) and aac(6’)-Ib-cr (14.1%) determinants was low. The qnr-genes were more prevalent in Klebsiella spp. (7.7%) than in E. coli (0.7%). qnrS1 was the most common qnr gene.The qnrS1 genes were located on at least three different plasmid backbones. Nevertheless, the qnrS1-containing area containd matching structures in all the qnrS1-positive isolates.
Author: Nabil Karah
Language: English
Subfield: Microbiology (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W1576977181