The Metabolism of Cyclopropane Fatty Acids by Tetrahymena pyriformis
Year: 1974
Type: article
Abstract: Cyclopropane fatty acids are readily metabolized by whole cells of Tetrahymena pyriformis when the fatty acids are presented either as components of intact Escherichia coli cells or as free fatty acids added to the medium. cis-11,12-[methylene-14C]Methyleneoctadecanoic acid was degraded with the production of 14CO2 by whole T. pyriformis cells or a particulate fraction derived from them. In the presence of malonate, [2-14C]acetate was formed. A pathway for degradation of the cyclopropane fatty acids, requiring only minor modification of the usual β oxidation pathway, is proposed.
Source: Journal of Biological Chemistry
Authors: Carl L. Tipton, Najah M. Al-Shathir
Institution: Iowa State University
Language: English
Subfield: Biochemistry
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $3,430
OpenAlex ID: W1587759727