Development of a Heterologous Model in Germfree Suckling Rats for Studies of Rotavirus Diarrhea
Year: 1998
Type: article
Abstract: Germfree suckling rats were infected with an SA11 rotavirus strain. Infected pups developed diarrhea associated with histopathological changes. The virus was detected in feces and in the small intestine. Cellular vacuolation was observed in the villi of the jejunum. These results provide a new model for further investigations of group A rotavirus infection.
Source: Journal of Virology
Authors: C. Guerin-Danan, J. C. Meslin, F. Lambre, A. Charpilienne, M. Serezat, C. Bouley, J. Cohen, C. Andrieux
Institutions: Virologie et Immunologie Moléculaires, Danone (France)
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Funder: Danone
OpenAlex ID: W1770109987