Evaluation of Antioxidant, Analgesic and Cytotoxic Activities of Typha angustata L. Root
Year: 2015
Type: article
Abstract: Ethanolic extract of the root of Typha angustata was evaluated for antioxidant, analgesic and cytotoxic activities. T. angustata extract exhibited DPPH free radical scavenging activity with IC50 value of 124.96 ± 0.93 ?g/ml. The total phenolic and tannin content were found to be 596.73 ± 1 mg GAE/100 g and 319.68 ± 64 mg GAE/100 g of dried plant material, respectively. Analgesic activity was determined using acetic acid induced writhing inhibition in mice model. The root extract, at doses of 250 mg/kg and 500 mg/kg body weight, showed inhibition of writhing reflex by 33.55% (p < 0.01) and 56.78% (p<0.001), respectively. Cytotoxicity of the extract was measured by brine shrimp lethality bioassay where the LC50 against brine shrimp nauplii was found to be 41.54?g/ml.Dhaka Univ. J. Pharm. Sci. 14(1): 55-59, 2015 (June)
Institution: Khulna University
Language: English
Topic: Medicinal Plant Research
Subfield: Plant Science
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W1786375596