Evaluación histopatológica del oído interno de curieles sometidos a toxicidad por estreptomicina y tratados con ozono
Year: 1998
Type: article
Abstract: The histopathological changes in the innear ear of guinea pigs after ototoxic damage with streptomycin sulfate and treatment with Ozone (O3) and oxygen (O2) was study. Celoidin and paraffin methods were employed. The group damage with 300 mg/kg streptomycin and treatment with O3 shown com-plete destruction of the sensory epithelium over the basilar membrane, atrophy of the stria vascularis and atrophy del limbus spiralis. In the rest of groups with ototoxic drugs (100 y 200 mg/kg) and treatment with O3 a reduction in the num-ber of damaged structure was found, however there were not morphological differences to compare with the group treated with O2. This findings provides a morphological basis for the concept that innear ear cell damage may be revers-ible under specific treatments.
Institution: Centro Nacional de Investigaciones Científicas
Language: Spanish
Subfield: Sensory Systems
Field: Neuroscience
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W188326482