Work

Shiga-like cytotoxin production by enteropathogenic Escherichia coli serogroups

Year: 1985

Type: article

Abstract: The mechanism by which enteropathogenic Escherichia coli (EPEC) cause disease remains to be defined. We studied EPEC and non-EPEC strains of E. coli from stool specimens obtained from infants and adults for production of Shiga-like cytotoxin. Although it was common for healthy infants and adults to have cytotoxin-producing E. coli as part of the fecal flora, Shiga-like cytotoxin was detected more commonly and in greater amounts among EPEC than among other fecal E. coli. These results suggest a role for Shiga-like cytotoxin in the pathogenesis of EPEC-related gastroenteritis.

Source: Infection and Immunity

DOI: 10.1128/iai.47.1.335-337.1985

Authors: T G Cleary, J J Mathewson, E Faris, L K Pickering

Language: English

Topic: Escherichia coli research studies

Subfield: Endocrinology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: Eunice Kennedy Shriver National Institute of Child Health and Human Development

Award: G3132075924