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Acute cerebral oedema induced by methotrexate: Authors' reply

Year: 1989
Type: letter
Abstract: haematoma as incidental.There was no computed tomogram before treatment, the aetiology of the haematoma was not discussed, and results of examination of the cerebrospinal fluid were not given.In addition, the second reference is in supplement 1 of Cancer 7reatment Reports 1981 and not in the main journal.Rather than postulate a second, previously un- reported cause of this patient's neurological con- dition it would be simpler to follow Occam's razor and explain that which is obvious.The intracerebral haematoma may have resulted from hypertension, aneurysm, or haemorrhage into a deposit, in which case the administration of metho- trexate would then probably be incidental.
Source: BMJ
Authors: Russell Lane, P J Hughes
Language: English
Field: Medicine
Open Access status: hybrid
OpenAlex ID: W1963740141
Cites: 4
Cited by: 1
Related to: 10