Year: 1956
Type: article
Abstract: NEW type of ovarian tumor, called by its A discoverer "fibroma papillare superficiale carcinomatosum ovarii," was described by Orthmann in 1899.A fuller description of this tumor type, under the designation "oophoroma folliculare," together with the addition of three more cases, was given eight years later by Fritz Rrenner.This tumor was subsequently popularized by Robert Meyer who pointed out its association with pseudoinucinous cysts, its lack of endocrine function, and its probable origin from Walthard's cell rests.He gave it the name by which it has since been known, the Brenner tumor, it being the only ovarian tumor having no pathological designation other than its eponymic.T h e first of Brenner's three cases reported in 1907 was that of a 62-year-old woman who had been known to have a small pelvic tumor for at least four years.A sudden spurt in its growth led to the presumptive clinical diagnosis of sarcomatous change in a inyomatous uterus, for which operation was undertaken, consisting of subtotal hysterectomy and right salpingo-oophorectomy.T h e tumor was confined to the right ovary, and a small amount of ascitic fluid was present in the abdominal cavity.T h e patient died eight days later from intestinal obstruction."The ovoid tumor," in Brenner's words, was "almost as large as a man's head . . .completely smooth on it5 surface.In places several parts project as thick, flat protuberances; the consistency is solid, corresponding somewhat to a moderately firm myoma.On cut surface one distinguishes a thin, firmly adherent capsule from the tumor parenchyma.One sees a solid, gray-yellow tumor mass, which in a few places shows small, smoothly lined cavities u p to the size of a cherry, into which the adjacent parts ol the tumor encroach as flat projections.In the yellow-gray parenchyma numerous rather light strands of connective tissue form a dense fibrous network, in which are embedded, in
Source: Cancer
Author: Harold Speert
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W1963929520