Work

β-Ketoacyl Acyl Carrier Protein Synthase III (FabH) Is Essential for Fatty Acid Biosynthesis in Streptomyces coelicolor A3(2)

Year: 2001

Type: article

Abstract: The Streptomyces coelicolor fab (fatty acid biosynthesis) gene cluster (fabD-fabH-acpP-fabF) is cotranscribed to produce a leaderless mRNA transcript. One of these genes, fabH, encodes a ketoacyl synthase III that is essential to and is proposed to be responsible for initiation of fatty acid biosynthesis in S. coelicolor.

Source: Journal of Bacteriology

DOI: 10.1128/jb.183.11.3526-3530.2001

Authors: W. Peter Revill, Maureen J. Bibb, Ann-Karolin Scheu, Helen J. Kieser, David A. Hopwood

Institutions: John Innes Centre, Norwich Research Park

Language: English

Topic: Lipid metabolism and biosynthesis

Subfield: Biochemistry

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: John Innes Foundation, Biotechnology and Biological Sciences Research Council

OpenAlex ID: W1965972464

FWCI: 0.956

Cites: 21

Cited by: 68

Related to: 10