Work

Effect of Intravenous Propranolol on Left Ventricular Apical Ballooning Without Coronary Artery Stenosis (Ampulla Cardiomyopathy). Three Cases.

Year: 2002

Type: article

Abstract: The precise etiological basis of transient left ventricular apical ballooning without coronary artery stenosis (ampulla or so-called 'takotsubo' cardiomyopathy) remains unknown, so the present study examined the acute effects of intravenous propranolol (2-4 mg) in 3 female patients (age range, 61-76 years) with the condition. Although one patient who did not have any intraventricular pressure gradients showed no improvement in the electrocardiographic and left ventricular wall motion abnormalities, the other 2 patients, who had significant intraventricular pressure gradients, did show improvement. Dynamic intraventricular obstruction might play a role in maintaining apical ballooning, at least, in patients exhibiting an intraventricular pressure gradient.

Source: Circulation Journal

DOI: 10.1253/circj.66.1181

Authors: Michifumi Kyuma, Kazufumi Tsuchihashi, Yasuyuki Shinshi, Mamoru Hase, Tomoaki Nakata, Hitoshi Ooiwa, Masayoshi Abiru, Nobuichi Hikita, Tateo Adachi, Tetsuro Shoji, Yukiyasu Fujise, Kazuaki Shimamoto

Institutions: Sapporo Medical University, Oji General Hospital, Muroran City General Hospital

Language: English

Topic: Takotsubo Cardiomyopathy and Associated Phenomena

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W1966476205

FWCI: 3.594

Cites: 21

Cited by: 137

Related to: 10