Year: 2010
Type: article
Abstract: Eosinophilic fasciitis is a rare sclerodermatous dis order with controversial etiology and pathogenesis. Constellation of clinical features and laboratory abnormalities establishes the di agnosis: deep induration of the subcutaneous tissue, flexion joint contractures, high eosinophil count in blood and bone marrow, characteristic histologic find ings, arthralgia, myalgia, negative visceral involvement, negative Raynaud phenomenon, history of excessive physical exercise, therapeutic sensitivity to corticosteroids and characteristic MRI findings. The main stay of treatment are systemic corticosteroids and early intervention is usually effective with a benign course of the disease. Refractory cases may require immunosuppressive or alternative agents. Scripta Scientifica Medica 2010;42(1):11-15
Source: Scripta Scientifica Medica
Authors: S. Marina, Kristina Semkova
Institution: Medical University of Varna
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W1968289165