Work

Effects of co-administration of monomethylaminoantipyrine and cobaltous chloride on hepatic glutathione level and glutathione-related enzyme activities in rats.

Year: 1987

Type: article

Abstract: Concurrent administration of monomethylaminoantipyrine (MAA) and CoCl2 caused a significant decrease of hepatic reduced glutathione and oxidized glutathione levels. Furthermore, the increase of glutathione S-transferase activity by combined treatment resulted in the decrease of Se-dependent glutathione peroxidase activity.

Source: The Japanese Journal of Pharmacology

DOI: 10.1254/jjp.43.335

Authors: Katsuji HOSHI, Naoto SENDA, Takashi IGARASHI, Tetsuo SATOH, Koichi UENO, Haruo KITAGAWA

Institutions: Chiba University, Tokyo College, The University of Tokyo

Language: English

Topic: Glutathione Transferases and Polymorphisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W1968483755