Concomitant presentation of acute myeloid leukemia with T-cell large granular lymphocytic leukemia
Year: 2007
Type: article
Study design: Case Report
Abstract: T-cell large granular lymphocyte leukemia (T-LGL) also known as T-cell chronic lymphocytic leukemia is rare and comprises a small minority of all small lymphocytic leukemias. The concomitant presentation of T-LGL with acute myeloid leukemia (AML) has not been previously reported. We present an elderly gentleman with concomitant T-LGL and AML (non-M3) diagnosed by a combination of morphologic evaluation, immunophenotyping by flow cytometry, and T-cell gene rearrangement studies. The patient was managed with combination AML chemotherapy. He remains alive and well seven months after initial diagnosis. A brief review of literature is also presented.
Source: Acta Oncologica
Authors: Ashok Kumar Malani, Chakshu Gupta, Rajgopal Rangineni, Jaswinder Singh, Hussam Ammar
Institution: Heartland Regional Medical Center
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W1969690339