Work

Novel Streptomycin Resistance Gene from Mycobacterium fortuitum

Year: 2006

Type: article

Abstract: We have isolated the aph(3")-Ic gene, encoding an aminoglycoside 3"-O-phosphotransferase [APH(3")-Ic], from a genomic library of an environmental Mycobacterium fortuitum strain, selecting for streptomycin resistance. APH(3")-Ic phosphorylates and inactivates streptomycin. Similar genes have been described in Streptomyces griseus and plasmid RSF1010. It is also present in some M. fortuitum clinical isolates.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.00223-06

Authors: Santiago Ramón-García, Isabel Otal, Carlos Martín, Rafael Gómez-Lus, José A. Aínsa

Institution: Universidad de Zaragoza

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Microbiology (medical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W1970045865

FWCI: 1.27

Cites: 23

Cited by: 36

Related to: 10