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Molecular biology of oral sub mucous fibrosis

Year: 2013

Type: article

Abstract: Oral sub mucous fibrosis is an insidious chronic disease affecting any part of the oral cavity. Worldwide estimates of oral sub mucous fibrosis indicate that 2.5 million people are affected, with most cases concentrated in the Indian subcontinent, especially eastern and southern India. Oral sub mucous fibrosis has a propensity for malignant transformation. The association of betel quid chewing, oral sub mucous fibrosis, and oral squamous cell carcinoma is quite profound, especially in Taiwan and the Indian subcontinent where up to 80% of oral squamous cell carcinoma is associated with the habit. Epidemiological studies have shown that the rate of malignant transformation ranges from 3 to 19%.

Source: Journal of Cancer Research and Therapeutics

DOI: 10.4103/0973-1482.113340

Authors: K Saravanan, MKodanda Ram, R Ganesh

Institutions: Vinayaka Missions University, Kannur Dental College, Kannur University, SRM Dental College

Language: English

Topic: Oral Health Pathology and Treatment

Subfield: General Dentistry

Field: Dentistry

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W1970367752

FWCI: 1.638

Cites:

Cited by: 15

Related to: 10