Year: 2012
Type: article
Abstract: Under the label of the German Mouse Clinic (GMC), a concept has been developed and implemented that allows the better understanding of human diseases on the pathophysiological and molecular level. This includes better understanding of the crosstalk between different organs, pleiotropy of genes, and the systemic impact of envirotypes and drugs. In the GMC, experts from various fields of mouse genetics and physiology, in close collaboration with clinicians, work side by side under one roof. The GMC is an open-access platform for the scientific community by providing phenotypic analysis in bilateral collaborations ("bottom-up projects") and as a partner and driver in international large-scale biology projects ("top-down projects"). Furthermore, technology development is a major topic in the GMC. Innovative techniques for primary and secondary screens are developed and implemented into the phenotyping pipelines (e.g., detection of volatile organic compounds, VOCs).
Source: Mammalian Genome
Authors: Helmut Fuchs, Valérie Gailus-Durner, Susanne Neschen, Thure Adler, Luciana Caminha Afonso, Juan Antonio Aguilar-Pimentel, Lore Becker, Alexander Bohla, Julia Calzada-Wack, Christian Cohrs, Anna Dewert, Barbara Fridrich, Lillian Garrett, Lisa Glasl, Alexander Götz, Wolfgang Hans, Sabine M. Hölter, Marion Horsch, Anja Hurt, Eva Janas, Dirk Janik, Melanie Kahle, Martin Kistler, Tanja Klein-Rodewald, Christoph Lengger, Tonia Ludwig, Holger Maier, Susan Marschall, Kateryna Micklich, Gabriele Möller, Beatrix Naton, Cornelia Prehn, Oliver Puk, Ildikó Rácz, Michael Räß, Birgit Rathkolb, Jan Rozman, Markus Scheerer, Evelyn Schiller, Anja Schrewe, Ralph Steinkamp, Claudia Stöger, Minxuan Sun, Wilfried Szymczak, Irina Treise, Ingrid Liliana Vargas Panesso, Alexandra M. Vernaleken, Monja Willershäuser, Annemarie Wolff-Muscate, Ramona Zeh, Jerzy Adamski, Johannes Beckers, Raffi Bekeredjian, Dirk H. Busch, Oliver Eickelberg, Jack Favor, Jochen Graw, Heinz Höfler, Christoph Höschen, Hugo Katus, Martin Klingenspor, Thomas Klopstock, Frauke Neff, Markus Ollert, Holger Schulz, Tobias Stöger, Eckhard Wolf, Wolfgang Wurst, Ali Önder Yildirim, Andreas Zimmer, Martin Hrabě de Angelis
Institutions: Helmholtz Munich, Technical University of Munich, TUM Klinikum, Ludwig-Maximilians-Universität München, Else Kröner Fresenius Zentrum für Ernährungsmedizin, University of Bonn, Heidelberg University, Institut für Humangenetik, Pathologisches Institut, German Center for Neurodegenerative Diseases, Max Planck Institute of Psychiatry, German Center for Diabetes Research
Language: English
Subfield: Small Animals
Field: Veterinary
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,890
Awards: Verbundprojekt: Deutsche Mausklinik - Teilprojekt 10, Verbundprojekt: Deutsche Mausklinik - Teilprojekt 7, G5768992294, Verbundprojekt: Deutsche Mausklinik - Teilprojekte 1, 3, 5, 6, 9, 11, 12, 15, 16, 18, Aufbau und Implementierung der deutschen Infrafrontier-Einrichtungen - Implementierungsphase 2, Verbundprojekt: Deutsche Mausklinik - Teilprojekt 13, Verbundprojekt: Deutsche Mausklinik - Teilprojekt 14, Verbundprojekt: Deutsche Mausklinik - Teilprojekte 2, 4
OpenAlex ID: W1973138306