Optimization of Synthesis Technology of Acetylferrocene by Response Surface Methodology
Year: 2012
Type: article
Abstract: Acetylferrocene was synthesized by acetyl chloride and ferrocene as raw materials, dichloromethane as the solvent, and ZnO as catalyst. Response surface methodology based on three-level, three-variable central composite rotable design was used to evaluate the interactive effects of the ratio of acetyl chloride and ferrocene(2-4), the amount of ZnO(1.0-1.3mol), reaction time(30-60 min)on the percentage yield of acylferrocene. The optimal raw material ratio, amount catalyst, and reaction time was 3:1, 1.19mol, 40min. Under the optimum conditions, the actual experimental yield can reach 86.72%.
Source: Advanced materials research
Authors: Da Wei Yin, Gang Tao Liang, Xiao Ming Sun, Yu Ting Liu
Institution: Shaanxi University of Science and Technology
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: hybrid
OpenAlex ID: W1978005568