Work

Non-replication of an association of Apolipoprotein E2 with sinistrality

Year: 2013

Type: review

Abstract: A recent report found that left-handed adolescents were more than three times more likely to have an Apolipoprotein (APOE) ϵ2 allele. This study was unable to replicate this association in young adults (N=166). A meta-analysis of nine other datasets (N=360 to 7559, Power > 0.999) including that of National Alzheimer's Coordinating Center also failed to find an over-representation of ϵ2 among left-handers indicating that this earlier outcome was most likely a statistical artefact.

Source: Laterality Asymmetries of Body Brain and Cognition

DOI: 10.1080/1357650x.2012.660164

Authors: Brian J. Piper, Alia L. Yasen, Amy E. Taylor, Jonatan R. Ruiz, J. William Gaynor, Catherine A. Dayger, Marcela Gonzalez-Gross, Oh D. Kwon, Lars-Göran Nilsson, Ian N. M. Day, Jacob Raber, Jeremy K. Miller

Institutions: Willamette University, Oregon Health & Science University, University of Bristol, Karolinska Institutet, Children's Hospital of Philadelphia, Universidad Politécnica de Madrid, Daegu Catholic University, Stockholm University

Language: English

Topic: Hemispheric Asymmetry in Neuroscience

Subfield: Cognitive Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Wellcome Trust, National Institute on Aging, National Institute on Drug Abuse, National Institute of Environmental Health Sciences, National Center for Research Resources

Awards: UC Davis Alzheimer's Disease Core Center, Biological Bases of Drug-Seeking Behavior, National Alzheimer's Coordinating Center, ALSPAC The Avon Longitudinal Study of Parents and Children: An international resource for population genomics and lifecourse epidemiology. Core Programme Support 2011-2013., Oregon Clinical and Translational Research Institute, G7486046685, Integrated Regional Training Program in Environmental Health Sciences (IRTP)

OpenAlex ID: W1978790260

FWCI: 0.131

Cites: 39

Cited by: 16

Related to: 10