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The continuous flow synthesis of butane-2,3-diacetal protected building blocks using microreactors

Year: 2010

Type: article

Abstract: The continuous flow synthesis of butane-2,3-diacetal protected derivatives has been achieved using commercially available flow chemistry microreactors in concert with solid supported reagents and scavengers to provide in-line purification systems. The BDA protected products are all obtained in superior yield to the corresponding batch processes.

Source: Organic & Biomolecular Chemistry

DOI: 10.1039/b924309g

Authors: Catherine F. Carter, Ian R. Baxendale, John B. J. Pavey, Steven V. Ley

Institutions: University of Cambridge, AstraZeneca (United Kingdom)

Language: English

Topic: Innovative Microfluidic and Catalytic Techniques Innovation

Subfield: Fluid Flow and Transfer Processes

Field: Chemical Engineering

Domain: Physical Sciences

Open Access status: green

Funder: AstraZeneca

OpenAlex ID: W1985609590

FWCI: 5.786

Cites: 47

Cited by: 49

Related to: 10