Work

Discovery of Inhibitors of Schistosoma mansoni HDAC8 by Combining Homology Modeling, Virtual Screening, and in Vitro Validation

Year: 2014

Type: article

Source: Journal of Chemical Information and Modeling

DOI: 10.1021/ci5004653

Authors: Srinivasaraghavan Kannan, Jelena Melesina, Alexander-Thomas Hauser, Alokta Chakrabarti, Tino Heimburg, Karin Schmidtkunz, Alexandra Walter, Martin Marek, Raymond J. Pierce, Christophe Romier, Manfred Jung, Wolfgang Sippl

Institutions: Martin Luther University Halle-Wittenberg, University of Freiburg, German Cancer Research Center, Deutsches Konsortium für Translationale Krebsforschung, Centre National de la Recherche Scientifique, Inserm, Institut de génétique et de biologie moléculaire et cellulaire, Université de Strasbourg, Institut Pasteur de Lille, Center for Infection and Immunity of Lille, Université Lille Nord de France

Language: English

Topic: Computational Drug Discovery Methods

Subfield: Drug Discovery

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: European Commission, Institut National de la Santé et de la Recherche Médicale, Université de Strasbourg, Centre National de la Recherche Scientifique, French Infrastructure for Integrated Structural Biology, Directorate-General for Research and Innovation

Awards: Anti-Parasitic Drug Discovery in Epigenetics, Schistosoma Epigenetics - Targets, Regulation, New Drugs, G654663749

OpenAlex ID: W1985678753

FWCI: 4.611

Cites: 50

Cited by: 63

Related to: 10