Lignosulfonate, a Water-solubilized Lignin from the Waste Liquor of the Pulping Process, Inhibits the Infectivity and Cytopathic Effects of Human Immunodeficiency Virusin Vitro
Year: 1989
Type: article
Abstract: Lignosulfonate (LS), a water-solubilized lignin obtained from the waste liquor of the pulping process of woods, has antiviral activity against the human immunodeficiency virus (HIV) in vitro.LS completely inhibited the HIV-induced cytopathic effect, the HIV-specific antigen expression, and syncytia formation at the concentrations of > 50 jig/ml.Furthermore, LS inhibited the reverse transcriptase activity in a cell-free system.A sugar-eliminated LS (LS-KL) also had the sameantiviral activities.Recently we have reported the inhibition of infectivity and cytopathic effect of HIV by
Institutions: The University of Tokyo, Yamaguchi University
Language: English
Topic: Lignin and Wood Chemistry
Subfield: Process Chemistry and Technology
Field: Chemical Engineering
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W1987680368