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Overwhelming Pneumococcal Sepsis in a Patient with Splenic Hypoplasia

Year: 2014

Type: article

Abstract: A 58-year-old female was admitted due to severe sepsis and multi-organ failure with a fulminant purpuric rash. Meropenem, vancomycin and levofloxacin were administered, although no focus of infection was detected. However, computed tomography revealed a profoundly hypoplastic spleen, and a blood smear detected Howell-Jolly bodies. Blood cultures grew Streptococcus pneumoniae (serotype 22F) three hours after admission. The patient was finally diagnosed as overwhelming pneumococcal sepsis with hyposplenism precipitated by splenic hypoplasia. Clinicians should pay attention to the splenic size and Howell-Jolly bodies in cases of sepsis of unknown origin.

Source: General Medicine

DOI: 10.14442/general.15.68

Authors: Kenichiro Yaita, Yohei Sakamoto, Kazuhiko Nakaharai, Yukihiro Yoshimura, Natsuo Tachikawa

Institution: Yokohama Municipal Citizen's Hospital

Language: English

Topic: Pneumonia and Respiratory Infections

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W1990879599

FWCI: 0.45

Cites: 11

Cited by: 4

Related to: 10