I. Mitt.: Mikrokinematographische Beobachtungen an kultivierten Mäuse-Omenten; Nachweis gebildeter Antikörper
Year: 1966
Type: article
Abstract: The greater omentum of the mouse — a transparent membranous organ — is especially suited for the direct and continous observation of immune reactions in vitro. Subsequent to intraperitoneal antigenic stimulation milky spots appear, which may be described as two-dimensional “immune-factories”. Methods have been developed for the cultivation of stimulated and nonstimulated omenta and for the prolonged observation of the cellular events by time-lapse microcinematography. It has not yet been possible to induce antibody formation in vitro; however, evidence of continued antibody synthesis was obtained for a period of 3—6 weeks in tissue culture. First observations of the cellular dynamics after primary stimulation in vivo and secondary stimulation in vitro are described.
Source: Zeitschrift für Naturforschung B
Authors: W. Ax, U. Kaboth, H. Fischer
Language: English
Topic: T-cell and B-cell Immunology
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $2,712
OpenAlex ID: W1995169778