Year: 2012
Type: article
Abstract: This paper deals with a chemotaxis-haptotaxis model of cancer invasion of tissue. The model consists of three reaction- diffusion- taxis partial differential equations describing interactions between cancer cells, matrix degrading enzymes, and the host tissue. The equation for cell density includes two bounded nonlinear density-dependent chemotactic and haptotactic sensitivity functions. In the absence of logistic damping, we prove the global existence of a unique classical solution to this model by some delicate a priori estimate techniques
Source: Applied Mathematics
Language: English
Subfield: Modeling and Simulation
Field: Mathematics
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W1996561990
