Acute thrombotic occlusion of the right coronary artery treated successfully with a helical thrombectomy device
Year: 2001
Type: article
Abstract: Objectives-To quantify the short term haemodynamic eVects of biventricular pacing in patients with heart failure and left bundle branch block by using three dimensional echocardiography.Design-Three dimensional echocardiography was performed in 15 consecutive heart failure patients (New York Heart Association functional class III or IV) with an implanted biventricular pacing system.Six minute walk tests were performed to investigate the eVect of biventricular pacing on exercise capacity.Data were acquired at sinus rhythm and after short term (2-7 days) biventricular pacing.Results-Compared with baseline values, biventricular pacing significantly reduced left ventricular end diastolic volume (EDV) by mean (SD) 4.0 (5.1)% (p < 0.01) and end systolic volume (ESV) by 5.6 (6.4)% (p < 0.02).Mitral regurgitant fraction was significantly reduced by 11 (12.1)%(p < 0.003) and forward stroke volume (FSV) increased by 13.9 (18.6)% (p < 0.02).Exercise capacity was significantly improved with biventricular pacing by 48.4 (43.3)% (p < 0.00001).Regression analyses showed that the percentage increase in FSV independently predicted percentage improvement in walking distance (r 2 = 0.73, p < 0.0002).Both basal QRS duration and QRS narrowing predicted pacing eYcacy, showing a significant correlation with % EDV, % ESV, and % FSV.Conclusions-In five of 15 consecutive patients with heart failure and left bundle branch block, biventricular pacing induced a more than 15% increase in FSV, which predicted a more than 25% increase in walking distance and was accompanied by an immediate reduction in left ventricular chamber size and mitral regurgitation.
Source: Heart
DOI: 10.1136/hrt.85.5.520
Authors: S CONSTANTINIDES, R JONES, M F SHIU
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W1996653151