“Classification of Therapy Resistance Based on Longitudinal Biomarker Profiles” by M. Kohlmann, L. Held and V. P. Grunert Biometrical Journal (2009) 51(4):610–626 Article: http://dx.doi.org/10.1002/bimj.200800157. Authors' reply: http://dx.doi.org/10.1002/bimj.201000119