Work

P01-022 – MEFV gene mutations registered to infevers

Year: 2013

Type: article

Abstract: Familial Mediterranean Fever (FMF) is the most common hereditary autoinflammatory disorder characterized by fever and abdominal pain. 16p13.3 chromosomally located MEFV gene has been responsible for disease outcome and its protein product, Pyrin, is the key regulator protein of inflammasome complex which leads to IL-1B production and inflammation.

Source: Pediatric Rheumatology

DOI: 10.1186/1546-0096-11-s1-a26

Authors: A Berdeli, S Nalbantoglu, D Tigli, I Demirel, M Atan

Institution: Ege University

Language: English

Topic: Inflammasome and immune disorders

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,090