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Isolation and Structure Elucidation of Five New Asterriquinones from Aspergillus, Humicola and Botryotrichum Species.

Year: 1996

Type: article

Abstract: Five new quinone pigments have been discovered from the fermentation broth of Aspergillus, Humicola and Botryotrichum species isolated from different soil samples. These compounds inhibit serine proteases of the coagulation pathway. Their structures which differ in the identity and position of a 5-carbon side chain on the indole moiety have been elucidated based on NMR and FAB-MS experiments.

Source: The Journal of Antibiotics

DOI: 10.7164/antibiotics.49.854

Authors: URSULA MOCEK, LAURI SCHULTZ, TIM BUCHAN, CHARLES BAEK, LARRY FRETTO, JERRY NZEREM, LOUIS SEHL, UMA SINHA

Language: English

Topic: Microbial Natural Products and Biosynthesis

Subfield: Pharmacology (medical)

Field: Medicine

Domain: Health Sciences

Open Access status: bronze

Funder: University of Washington

OpenAlex ID: W1998388391

FWCI: 1.457

Cites: 12

Cited by: 27

Related to: 10